Man shafawa na Sodium Stearyl Fumarate (SSF) | Babban karfin API, Madadin Magnesium Stearate, GMP Grade

Sodium Stearyl Fumarate (SSF) wani man shafawa ne mai tsafta wanda aka tsara musamman don maganin ƙwayoyin cuta da ƙwayoyin cuta. Ba kamar magnesium stearate ba, yana ba da kyakkyawan jituwa da API, ƙarfi ga yawan shafawa, kuma ba shi da wani mummunan tasiri ga samuwar halittu.Man shafawa ne mai ruwa-ruwa mai narkewa wanda ke samar da taurin kwamfutar hannu mai kyau a daidai ƙarfin matsi kuma yana rage tasirin lokacin wargajewa.Ya yi daidai da magungunan USP-NF, EP, da JP tare da rajistar CDE (F20190000009) da tallafin DMF (38822). Matsayin amfani da aka ba da shawarar: 0.5-3% w/wYa dace da manyan allunan matsawa kai tsaye, da kuma ƙwayoyin da ba su dace da APIs ba.

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Sodium Stearyl Fumarate (SSF)

Bayanin Samfuri

Sodium Stearyl Fumarate (SSF) wani man shafawa ne mai inganci wanda aka san shi sosai a matsayin madadin man shafawa na gargajiya kamar magnesium stearate da talc.Gishirin sodium ne na stearyl fumaric acid, yana bayyana a matsayin foda mai laushi daga fari zuwa fari tare da halayen amphiphilic wanda ke ba da damar yin amfani da man shafawa mai inganci a cikin ƙwayoyin cuta da ƙwayoyin magani..

Asalin Samfuri:

Sunan Sinadarai:Sodium Stearyl Fumarate
Lambar CAS:4070-80-8
Lambar Rijistar CDE:F20190000009
Lambar DMF:38822
Bin ƙa'idodin Pharmacopoeia:USP-NF, EP, JP
Tsarin Kwayoyin Halitta:C22H39NaO4
Nauyin kwayoyin halitta:390.53 g/mol

Muhimman Abubuwa & Fa'idodi

1. Mafi kyawun Dacewa da API

Yana magance matsalolin jituwa da ake yawan fuskanta tare da magnesium stearate.
Rashin jituwar API da magnesium stearate sun haɗa da: Azathioprine, Cefaclor, Cilazapril, Clopidogrel, Diclofenac, Ibuprofen, Omeprazole, da sauransu da yawa.
Ya dace da dabarun da rashin jituwar sinadarai ke damun su

2. Ƙarfi zuwa Yawan Man Shafawa

Ba kamar magnesium stearate ba, SSF yana kiyaye aiki koda kuwa akwai tsawaita lokacin haɗawa
Yana samar da tauri da wargajewar kwamfutar hannu ba tare da tasirin "mai danshi fiye da kima" ba

3. Ingantaccen Halayen Kwamfutar hannu

Taurin kai mafi girmaa daidai ƙarfin matsi idan aka kwatanta da sauran man shafawa
Ƙarancin tasiri akan lokacin wargajewa- yana kiyaye saurin rugujewar kwamfutar hannu
Babu wani mummunan tasiri akan bioavailability- yana tabbatar da cewa bayanan sakin magunguna sun kasance daidai

4. Yanayi Mai Ruwa Mai Kyau da Rabin Narkewa

Man shafawa mai narkewar ruwa - 0.5 mg/100 mL a 25°C, yana ƙaruwa zuwa 20 g/100 mL a 90°C
Yana haifar da ƙarancin ragowar da ke cikin maganin, wanda hakan ya sa ya dace daAllunan effervescent
Yana inganta bayanan rushewar APIs marasa narkewa sosai

5. Kyawawan Halayen Jiki